| abstract |
The present invention relates to benzenesulfonyl (thio) ureas of formula (I), their optional stereoisomeric forms and mixtures thereof and / or physiologically acceptable salts thereof for the preparation of a medicament for the treatment or prevention of autonomic nervous system disorders, wherein R 1 is hydrogen, , alkyl, alkoxy, alkoxyalkoxy, alkoxyalkoxyalkoxy, alkylthio, fluoroalkoxy, or fluoroalkyl, E is oxygen or sulfur, Y is - (CR32) n-, wherein R3 is independently at each occurrence or alkyl; , n is 1, 2, 3 or 4, X is hydrogen, halogen or alkyl, Z is halogen, nitro, alkoxy or alkyl, optionally in beta or in combination with a blocker. The invention relates to products and pharmaceutical compositions containing the above compounds. SHE |