| abstract |
The present invention provides compounds of formula (I) wherein the substituents have the meanings given below. The compounds have antiarrhythmic properties and have a cardioprotective component. The compounds of the present invention may inhibit or inhibit pathophysiological processes induced by ischemic or cardiac arrhythmias, particularly prior to or prior to the onset of ischemic injury. R 2 and R 3 are hydrogen, halogen, hifluoromethyl, cyano, alkyl, nitro, alkoxyalkyl, alkoxy or hydrogen, alkyl, optionally substituted alkylphenyl, alkylheteroaryl, alkylcycloalkyl; alkylcarbonyl, or alkylphenyl, alkylheteroaryl; R4 is -SOp-R16 where p is 0, 1 or 2; R16 is alkyl or optionally substituted phenyl. |