http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-0102607-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4dac022280ec96f54c694eb427655932 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
| filingDate | 1999-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6e0dddc4d367c2d620a7b7dc74f2f41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d6c265913b189a8bcd3bcb53e68f807 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba9695f185ed54d131f8bbad733c8435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eed485199211a76c468e78ec966585a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a89c95bbac657c4ca39599fda25484e2 |
| publicationDate | 2002-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-0102607-A2 |
| titleOfInvention | Sulphonyl-substituted biphenylmethyl imidazole derivatives, pharmaceutical compositions containing them and their use |
| abstract | In the general formula (I) of the antiarrhythmic compounds of the present invention, R (1) is hydrogen, alkyl or -CaH2a-phenyl optionally substituted in the phenyl moiety where a is 0, 1 or 2, or R (1) is -CbH2b-heteroaryl. which may be optionally substituted on its heteroaryl, wherein b is 0, 1 or 2, or R (1) is -CdH2d-cycloalkyl, wherein d is 0, 1 or 2, R (2) and R (3) are independently hydrogen, fluorine, chlorine, bromine, iodine, trifluoromethyl, cyano, nitro, -CH2OR (17), -CO-R (6), -OR (7), -O- (alkylene) -OR ( 17) or -NR (50) R (51) where R (17) is hydrogen or alkyl, R (6) is hydrogen, alkyl, -OR (30) or phenyl, which may be optionally substituted. , wherein R (30) is hydrogen or alkyl, R (50) and R (51) independently of one another - (alkylene) -OR (52) - wherein R (52) is hydrogen or alkyl, R (7) is hydrogen, alkyl or phenyl, which may be optionally substituted, or R (7) is heteroaryl, which may be optionally substituted, or R (2) and R (3) independently of one another are alkyl, cycloalkyl or -CgH2g-phenyl optionally substituted in the phenyl moiety with 0, 1 or 2, or R (2) and R (3) independently of one another are -ClH 211 -heteroaryl, which may be optionally substituted on their heteroaryl moiety, wherein l is 0, 1 or 2, or R (2) and R (3) independently of one another are -SOn-R Wherein n is 0, 1 or 2, R (22) is alkyl, cycloalkyl or -CsH2s-phenyl optionally substituted in the phenyl moiety het, where 0 is 1 or 2, R (4) and R (5) independently of one another are hydrogen, alkyl, fluoro, chloro, bromo, iodo, trifluoromethyl, cyano, nitro, -SOp-R (16). , -CO-R (23), -OR (24) or -O- (alkylene) -OR (33) wherein p is 0, 1 or 2, R (16) is alkyl or phenyl optionally may be substituted where R (23) is hydrogen, alkyl or -OR (25) wherein R (25) is hydrogen or alkyl, R (24) is hydrogen, alkyl or phenyl optionally substituted with R (33). ) is hydrogen or alkyl, provided that at least one of R (2) and R (3) is -O- (C 2, C 3 or C 4 alkylene) -OR (17) or -NR (50) R (51) a group of the general formula. The invention includes physiologically acceptable salts of the above compounds and the above |
| priorityDate | 1998-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 306.