| abstract |
The present invention relates to hygromycin A derivatives. The present invention relates to compounds of general formula (I) and pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R 1 and R 2 are as defined herein. The compounds of formula (I) are antibacterial and antiprotozoal agents which can be used to treat various bacterial and protozoal infections and related disorders. The invention also relates to pharmaceutical compositions containing the compounds of formula (I) and to the manufacture of a medicament for the treatment of bacterial and protozoal infections. SHE |