| abstract |
The present invention relates to compounds of formula I, wherein A is a direct bond or -CH2O-; B is a direct bond or oxo; D - (CH 2) n - or -CH 2 CHOHCH 2 -; R is -NR1R2 or -NR1R2R3X, wherein X is an anion; and R 1, R 2 and R 3 are each independently hydrogen or C 1 -C 4 alkyl, or a non-toxic pharmaceutically acceptable salt or solvate thereof, and pharmaceutical compositions containing them for the treatment of disorders sensitive to potassium channel opening activity. SHE |