abstract |
The present invention relates to an aerosol pharmaceutical composition comprising: A) a therapeutic agent in particulate form coated with at least one coating excipient, namely lactose or trehalose, and at least one surfactant, and b) a mono-liquid propellant, 1,1,1,2-tetrafluoroethane; 1,1,2,3,3,3-heptafluoropropane or a mixture thereof. The invention also relates to the preparation of the above aerosolized pharmaceutical compositions, the particles contained therein and the cartridges containing the aerosolized pharmaceutical composition. The compositions are useful for the treatment of respiratory diseases. SHE |