| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ef8acc27b4252e343aa5da877c870d2 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-536
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2059
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-536
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 |
| filingDate |
1999-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce5a38d8d2664def836ced675f2725fe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6a59448a97d5da61fe564d55bc5a6ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78fb91a00d350955590afadeb1dac85d |
| publicationDate |
2001-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
HU-0101517-A2 |
| titleOfInvention |
Rapidly soluble capsules and tablets containing the active substance efavirenz, and a method for their preparation |
| abstract |
The capsules and tablets of the present invention contain an effective amount of a disintegrant additive in an amount of greater than about 10% by weight of efavirenz and the total dry solids content of the dosage form. These capsules and tablets are prepared by the process of the invention by wet granulating the efavirenz and the sodium starch glycolate portion of the granules in a high shear granulator using an aqueous solution of sodium lauryl sulfate; drying and grinding the resulting material; the resulting material is dry blended with the non-sodium starch glycolate particle and other pharmacologically acceptable excipients, and the resulting material is encapsulated or tableted. The capsules and tablets of the present invention are useful for inhibiting the activity of an immunodeficiency virus (HIV) in the human body and for treating an immunodeficiency condition (AIDS) resulting from HIV infection. SHE |
| priorityDate |
1998-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |