http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-0101356-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94ff2d78578d95d1e8d3a2233c76188d |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06 |
filingDate | 1999-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffecf7eadee3a440f1b5c9bda7cde7a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_302da4e2369037c31450127349df56b6 |
publicationDate | 2002-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | HU-0101356-A2 |
titleOfInvention | Process for the preparation of 1,3-disubstituted-4-oxo-cyclic ureas |
abstract | The present invention relates to a process for the preparation of 1,3-disubstituted-9-oxocyclic ureas of the general formula wherein R 1, R 2 and R 3 are independently hydrogen, amino, nitro, carboxy, mesylamino, sulfo, hydroxy, alkoxy. , alkyl, alkoxycarbonyl, hydroxyalkyl, carboxyalkyl or acyloxy; R4 is substituted or unsubstituted alkyl, alkenyl, alkynyl, alkyl acyl or heteroalkyl; and A is substituted or unsubstituted, saturated or unsaturated, straight or branched alkyl or alkenylamino; or a heterocyclic group containing at least one nitrogen atom, and R 4 is attached to this nitrogen atom. 1,3-Disubstituted-4-oxo-cyclic urea is prepared by (a) reacting a 1-substituted-4-oxo-cyclic urea with a carbon dioxide containing at least two leaving groups in the presence of a weak base and a solvent; and then (ib) condensing the adduct with an amine to 1,3-disubstituted-4-oxo-cyclic urea; and ii) recovering the product from the reaction mixture. SHE |
priorityDate | 1998-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 102.