| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92e8ce22e30c1fabac3f3cc214b9bfc4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-44 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-907
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
1999-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89f65528f483edb6315200e0bac402ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5687e1f31b5fdaf683d193b6dbfd9e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd2d0b09d927dcf9475b17d9cfbedb5e |
| publicationDate |
2001-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
HU-0101355-A2 |
| titleOfInvention |
Genomic sequences for protein production and targeting |
| abstract |
This invention relates to genomic DNA. More particularly, the present invention relates to DNA constructs capable of altering endogenous G-CSF gene expression upon integration into a mammalian cell genome. The DNA constructs of the invention contain targeting and transcriptional control sequences. The present invention further provides isolated nucleic acid molecules comprising a genomic sequence or fragments thereof 5 'to the coding region of the G-CSF gene, cells containing homologous recombination transformed with the DNA constructs of the invention, and methods for altering expression of the endogenous G-CSF gene. -CSF protein. The invention also provides the use of the nucleic acid molecules of the invention for the preparation of a pharmaceutical composition for delivery of G-CSF protein. The present invention is useful in the treatment and prevention of disorders associated with G-CSF expression. SHE |
| priorityDate |
1998-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |