| abstract |
The present invention provides compounds of formula I wherein R * X is CR'R ', NR', oxy or thio; Y is CR'R ', NR', oxy-thio; H, halogen, -ORg, -SRg, cyano, -NRgRk, nitro, trifluoromethyl, -S (O) rCF3, -CO2Rg, -CORg, -CONRg2, alkyl, Ar- (O- C 6 alkyl, Het (C 0-6 alkyl), (cycloalkyl) C0-6 alkyl, -S (O) k R8 or -CH2 N (Rf) 2; R 2 is or a pharmaceutically acceptable salt thereof. The invention also relates to novel intermediates of the compounds, to processes for the preparation of the compounds of the invention, to pharmaceutical compositions containing them and to their use in medicine. SHE |