abstract |
The present invention relates to compounds of formula (I), pharmaceutically acceptable salts and solvates thereof, to a process for the preparation of the compounds and to pharmaceutical compositions containing them, wherein X represents an oxygen atom, a sulfur atom or an -NH-, -CH2-, -CH2CH2- or -OCH2- group, Y -CH2 - or -CO-, R1 is pyridyl (preferably 3- or 4-pyridyl) or pyrimidinyl, and R2 is phenyl, pyridyl or pyrimidinyl, any of which may be optionally substituted with one or more identical or different substituents, namely halogen, amino, cyano. -, hydroxyl, nitro, C 1-6 alkyl, halogenated C 1-6 alkyl, C 1-6 alkoxy, (C 1-6 alkyl) thio, (di) - (C 1-6 alkyl) ) amino, (C 1-6 alkyl) carbonyl, (C 1-6 alkoxy) carbonyl, (C 1-6 alkyl) sulfinyl or (C 1-6 alkyl) sulfonyl or -NR 3 SO 2 R 4 , -SO2NR5R6 or -Z- (CH2) pZ- (C H2) q-H may be attached. SHE |