| abstract |
The present invention relates to the use of combinations of an α-adrenergic receptor antagonizing agent and acyclic 3 ′, 5′-monophosphate (cGMP) to enhance impotence, and to pharmaceutical compositions and kits particularly useful for treating patients with impotence or erectile dysfunction. According to the invention, an α-adrenergic antagonist compound and a cGMP concentration increasing compound are used together to treat impotence in the preparation of a suitable pharmaceutical composition. The compositions of the invention include a first compound selected from α-adrenoceptor antagonists, a second compound selected from compounds that increase cGMP concentration, and a pharmacologically acceptable carrier. SHE |