abstract |
The present invention relates to a composition comprising an E6 and / or E7 protein or E6 / E7 fusion protein linked to an HPV functional fusion partner, and a CpG-containing oligonucleotide. The present invention further provides a pharmaceutical composition and methods for preparing the present invention. The composition according to the invention can be used in a patient to induce an HPV antigenic immune response, and to prevent and treat HPV-induced tumors. HE |