| abstract |
The present invention relates to sulfonamide derivatives of the formula I, which are inhibitors of bone resorption and cell adhesion. In the formula (I), R1, R2, R4, R5 and R6 are as defined in the claims. The present invention relates to physiologically acceptable salts and prodrugs of the compounds. The compounds of formula I are valuable compounds, vitronectin receptor antagonists and inhibitors of bone resorption and cell adhesion induced by bone eating cells. They are suitable, for example, for the prevention and treatment of diseases which are partially unwanted by bone resorption, e.g. causes osteoporosis. The invention also relates to the preparation of compounds of the formula I, and in particular to their use as a pharmaceutical active ingredient, and to pharmaceutical compositions containing them. SHE |