| abstract |
The present invention relates to compounds of formula I wherein R 1 and R 2 alkyl are: R 3 is hydrogen, halo or alkyl at the 3-, 4- or 5-position; R4 is hydrogen or alkyl; The imino group (-NH-) or the oxygen atom attached to the X-heterocycle at the 4- or 7-position and their pharmaceutically acceptable salts, for use in the preparation thereof, for the preparation of medicaments for the treatment or prevention of gastrointestinal diseases, and for the preparation thereof. SHE |