http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-0002189-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aac141a3051e128a54ab3843e7aa47e2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D313-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 |
| filingDate | 1998-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02edfdfb54d249a1c4f929fcc1739498 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eddb48e9573a3764651bab818369225b |
| publicationDate | 2001-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-0002189-A2 |
| titleOfInvention | A method for the preparation of side-modified epothilones and the compounds thus prepared |
| abstract | The present invention relates to a process for the preparation of modified epothilones at position 16.17. The process consists of either protecting the 3.7-protected or unprotected epothilones A and H at position 3,77 by either a) hydrogenation of the 16,17 double bond, or b) halogenation of the 16,17 double bond, or c) They are epoxidized at the 16,17-double bond and optionally reduced to the 16-alcohol. The invention further relates to a process for the preparation of epothilone N-oxides, wherein the corresponding epothilones A or B are converted to N-oxides and optionally O-alkylated. Azepothilones are compounds useful in medicine. SHE |
| priorityDate | 1997-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.