http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-0001518-A2
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 |
| filingDate | 1997-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a753c550a18e356ce7c413accec7bd5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bcf72966e606994fe9709ab3a71ce3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31f43855b44b7da4ec58c5e1ef183af6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b50341cd500a89d5f1afff16a8b7df1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_998c44ee5bd694d58edfbef5f47b12f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ee3bb9051ffda47dec111ca539830d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6ae224073fa9ba2acc22ba3a80c75b8 |
| publicationDate | 2000-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-0001518-A2 |
| titleOfInvention | Tricyclic erythromycin derivatives |
| abstract | The present invention relates to compounds of general formulas (I), (II), (III) and (IV), and pharmaceutically acceptable salts and esters thereof, wherein A, B, D and E are each independently (a) hydrogen; (b) optionally substituted C 1-6 alkyl, (c) C 3-7 cycloalkyl; (d) aryl; (e) substituted aryl; (f) heteroaryl; (g) substituted heteroaryl. (h) heterocyclic alkyl; and (i) a substituent (b) above, which is still substituted, and any pair of substituents AB, AD, AE, BD, BE, or DE together with atom, atom or atom. to which they are attached may also form a 3- to 7-membered ring, which in each case also contains one or more heterofunctional piperidines; R1 is (a) hydrogen: (b) hydroxy; (c) -O-C 1-3 alkyl; (d) -O-C 3 -C 5 cycloalkyl; (e) -O-C 1-3 -alkyl-C 1-3 -cycloalkyl; (f) -O-C (O) -1-3 alkyl; (g) -O-C (O) -O-C 1-3 alkyl; and (h) alkyl-piperidine having a carbon number of -O-C (O) -NH-1-3; R2 is hydrogen or hydroxy protecting tube, and Z is hydroxy or protected hydroxy tube, with azala bond, so that the compound corresponds to the general formula (I), (II) or (III), but not A, B, D and E may be hydrogen, D and E may not be C 1 -C 3 alkylpipero, if A and B are hydrogen, and one of D and E must not be hydrocarbon and the other is C 1 -C 3 alkyl, if A and B are hydrogen. The present invention is also directed to pharmaceutical compositions containing the compounds of the general formula (I), (II), (III) or (IV) as pharmaceutically active salts. The compounds of the invention have antibacterial activity. ŕ |
| priorityDate | 1997-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.