http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-0001434-A2
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
filingDate | 1998-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_827312505d6edb9a79e2818d881964a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d47da21018e4b4ae930f8e1984739d65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_babfede42887462639fc565d22234b94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46e4cfbaf64d4dc196e92607f43f20c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a310b2fcd14c97232072685e117313a8 |
publicationDate | 2000-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | HU-0001434-A2 |
titleOfInvention | 5,7-Disubstituted 4-aminopyrido [2,3-d] pyrimidine compounds, pharmaceutical compositions containing them and a process for their preparation |
abstract | The present invention relates to a compound of formula (I) wherein R1 and R2 are independently hydrogen, lower alkyl, (C1-C6) alkoxy (C1-C6) alkyl, aryl (C1-C6) alkyl, , -C (O) -1-6 alkyl, -C (O) -aryl, -C (O) -heterocyclic, or together with the nitrogen to which they are attached form a 5-7 membered ring which optionally 1-2 more heteroatoms, namely oxygen, nitrogen and / or sulfur; R3 is lower alkyl, lower alkenyl, lower alkynyl, cycloalkyl, aryl, arylalkyl, heteroaryl, heterocyclic, heteroarylalkyl or heterocycloalkyl wherein the heteroaryl and heterocyclyl are directly they are indirectly attached through a ring carbon atom; R4 is lower alkyl, lower alkenyl, lower alkynyl, cycloalkyl, aryl, arylalkyl, heteroaryl, heterocyclic, heteroarylalkyl or heterocycloalkyl; and the dashed line - - - optionally double bond, provided that normal valencies are maintained - and an adenosine kinase inhibitor pharmaceutical composition comprising a therapeutically effective amount of a compound of formula (I) and a pharmaceutically acceptable carrier. Thus, the above compound can be used in the preparation of anti-cerebral ischemia, epilepsy, analgesia, inflammation and sepsis. The invention also extends to the preparation of compounds wherein R1, R2, R3 and R4 are as defined above. HE |
priorityDate | 1997-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1246.