http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-0000768-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a717ea5b2ac78ac329ab3a9659d834d2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-06 |
| filingDate | 1997-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_790c612e0f8532453d4d1551654a4d4d |
| publicationDate | 2001-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-0000768-A2 |
| titleOfInvention | Substituted benzo [1,4] dioxanes, a process for their preparation and pharmaceutical compositions containing them |
| abstract | The present invention relates to novel substituted 1,4-benzodioxane compounds of formula II having anti-diabetic, antihyperglycemic and anti-obesity properties, wherein R1 and R6 are independently hydrogen, alkyl, trifluoromethyl, cyano, alkoxy or halogen; R2 is hydrogen or trytalkylsilyl; R3 is hydrogen or alkoxycarbonyl; or R2 and R3 together form an oxazolidinone ring of formula (III); R4 and R5 are independently selected from the group consisting of hydrogen and alkyl; R7 and R8 are independently OR9 or NR10R11; R 9 is hydrogen, alkyl, cycloalkyl, silylalkyl, phenyl, naphthyl, phenylalkyl or alkoxyalkyl, pyridyl, thiophenyl, furanyl, imidazolyl, oxazolyl or -CHR 12 COOR 13, -CHR12C (O) R13, -CHR12CONR10R11, -CHR12OCOOR13, or-CHR12OC (O) R13; R10 and R11 are each independently hydrogen, alkyl, phenyl, naphthyl, phenylalkyl, furanylalkyl or alkoxycarbonite alkyl; R12 and R13 are each independently hydrogen, alkyl, phenyl, naphthyl or phenylalkyl; pharmaceutically acceptable salts, enantiomers, racemic mixtures, diastereomeric mixtures and salts thereof. The invention further relates to pharmaceutical compositions containing the above compounds and to a process for the preparation thereof. HE |
| priorityDate | 1996-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.