| abstract |
Compound: 5-Biphenyl-4-yl-3-hydroxy-2- [2- (4-oxo-1,2,3-benzotriazin-3 (4H) -yl) ethyl] pentanoic acid (Compound No. 1), 2- (2 - {[(Benzyloxy) carbonyl] amino} ethyl) -5-biphenyl-4-yl-3-hydroxypentanoic acid (Compound No. 11), 5-Biphenyl-4- yl-3-hydroxy-2- {2 - [(phenylacetyl) amino] ethyl} pentanoic acid (Compound No. 45), 5-Biphenyl-4-yl-3-hydroxy-2- [2- (1-oxophthalazine- 2 (1H) -yl) ethyl] pentanoic acid (Compound No. 47), 5-Biphenyl-4-yl-3-hydroxy-2- [2- (2'-oxospiro [cyclopropane-1,3'-indole]] -1 '(2'H) -yl) ethyl] pentanoic acid (Compound No. 49), 3-Hydroxy-2- [2- (4-oxo-1,2,3-benzotriazin-3 (4H) -yl) ethyl] -5- [4 '- (trifluoromethyl) biphenyl-4-yl] pentanoic acid (Compound No. 59), 5- (3', 4'-Difluorobibenyl-4-yl) -3-hydroxy-2- [2- (4-oxo-1,2,3-benzotriazin-3 (4H) -yl) ethyl] pentanoic acid (Compound No. 60), 3-Hydroxy-5- (4'-methoxybiphenyl-4-yl) -2- [2- (4-oxo-1,2,3-benzotriazin-3 (4H) -yl) ethyl] pentanoic acid (Compound No. 64), 5- (4'-chlorobiphenyl-4-yl) - 3-hydroxy-2- [2- (4-oxo-1,2,3-benzotriazin-3 (4H ) -yl) ethyl] pentanoic acid (compound no. 65), 3-Hydroxy-5- [4- (6-methoxypyridin-3-yl) phenyl] -2- [2- (4-oxo-1,2,3-benzotriazin-3 (4H) -yl) ethyl ] pentanoic acid (Compound No. 67), 3-Hydroxy-5- (4'-methylbiphenyl-4-yl) -2- [2- (5-methyl-1,3-dioxo-1,3-dihydro-2H) -isoindol-2-yl) ethyl] pentanoic acid (Compound No. 68), 5- (4'-chlorobiphenyl-4-yl) -3-hydroxy-2- [2- (5-methyl-1,3-dioxo) -1,3-dihydro-2H-isoindol-2-yl) ethyl] pentanoic acid (Compound No. 69), 3-Hydroxy-2- [2- (4-oxo-1,2,3-benzotriazin-3) 4H) -yl) ethyl] -5- [4 '- (trifluoromethoxy) biphenyl-4-yl] pentanoic acid (Compound No. 70), 5- (4'-Fluorobiphenyl-4-yl) -3-hydroxy-2 - [2- (4-oxo-1,2,3-benzotriazin-3 (4H) -yl) ethyl] pentanoic acid (Compound No. 71), 3-hydroxy-5- (4'-methylbiphenyl-4-yl) ) -2- [2- (4-oxo-1,2,3-benzotriazin-3 (4H) -yl) ethyl] pentanoic acid (Compound No. 72), 5- (4'-Cyanobiphenyl-4-yl) -3-hydroxy-2- [2- (4-oxo-1,2,3-benzotriazin-3 (4H) -yl) ethyl] pentanoic acid (Compound No. 73), 5- (4'-Fluorobiphenyl-4) -yl) -3-hydroxy-2- [2- (5-methyl-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl) ethyl] pentanoic acid (s sing no. 74), 3-Hydroxy-5- [4- (6-methoxypyridin-3-yl) phenyl] -2- [2- (5-methyl-1,3-dioxo-1,3-dihydro-2H-isoindole- 2-yl) ethyl] pentanoic acid (Compound No. 75), 5- (4'-Ethylbiphenyl-4-yl) -3-hydroxy-2- [2- (4-oxo-1,2,3-benzotriazin- 3 (4H) -yl) ethyl] pentanoic acid (Compound No. 76), 3-Hydroxy-2- [2- (5-methyl-1,3-dioxo-1,3-dihydro-2H-isoindole-2- yl) ethyl] -5- [4 '- (trifluoromethyl) biphenyl-4-yl] pentanoic acid (Compound No. 77), 5-Biphenyl-4-yl-3-hydroxy-2- [2 - (- oxo- 4-phenyl-4a, 8a-dihydrophthalazin-2 (1H) -yl) ethyl] pentanoic acid (Compound No. 84), 5-Biphenyl-4-yl-3-hydroxy-2- [2- (3-oxo) -2,3-dihydro-4H-1,4-benzoxazin-4-yl) ethyl] pentanoic acid (Compound No. 85), 5-Biphenyl-4-yl-2- {2 - [(3aR, 7aS) - 1,3-dioxo-1,3,3a, 4,7,7a-hexahydro-2H-isoindol-2-yl] ethyl} -3-hydroxypentanoic acid (Compound No. 86), 5-Biphenyl-4-yl- 2- (2 - [((4-fluorophenyl) sulfonyl] amino) ethyl) -3-hydroxypentanoic acid (Compound No. 87), 5-Biphenyl-4-yl-2- (2 - {[(3-fluorophenyl) acetyl] amino} ethyl) -3-hydroxypenta |