http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HR-P20120124-T1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f52c68e4149a6c462b850d4e7cc2b2f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-78 |
| filingDate | 2012-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f15286f68a70100ba9fa87fbf8f2b323 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77c0e7ff16ea5d9290f97485daed2d71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b033a681416bfb14fc853cfe25bfc1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9f0df80847e7551e67fe3101621ec61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_386824e41a5cb6d28f4287c02ef2c37d |
| publicationDate | 2012-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HR-P20120124-T1 |
| titleOfInvention | BENZYLAMINES, PROCEDURE FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY PRODUCTS |
| abstract | Stereoisomers of the general formula I in which R 1 and R 2 independently of one another represent hydrogen, a hydroxyl group, a halogen atom, an optionally substituted (C 1 -C 10) -alkyl group, an optionally substituted (C 1 -C 10) -alkoxy group, (C 1 -C 10) -alkylthio group, (C1-C5) -perfluoroalkyl group, cyano group, nitro group, or R1 and R2 together represent a group selected from the group consisting of -O- (CH2) pO-, -O- (CH2) p -CH2-, -O-CH = CH-, - (CH2) p + 2-, -NH- (CH2) p + 1, -N (C1-C3-alkyl) - (CH2) p + 1 and -NH -N = CH-, where p = 1 or 2, and the terminal oxygen atoms and / or carbon atoms and / or nitrogen atoms are attached directly to adjacent ring carbon atoms, or NR7R8, where R7 and R8, independently of one another, represent hydrogen , C1-C5-alkyl or (CO) - (C1-C5) -alkyl, R3 represents a hydrogen atom, a hydroxyl group, a halogen atom, a cyano group, an optionally substituted (C1-C10) -alkyl group, (C1-C10) - alkoxy group, (C1-C10) -alkylthio group, or (C1-C5) -perfluoroalkyl group, R4 represents monoc cyclic or bicyclic, aromatic, partially aromatic or non-aromatic ring system, optionally containing 1-4 nitrogen atoms, 1-2 oxygen atoms and / or 1-2 sulfur atoms and optionally substituted at one or more sites by a radical selected from a group consisting of carbonyl, halogen, hydroxy or (C1-C5) -alkyl, which may be optionally substituted by 1-3 hydroxy groups, 1-3 (C1-C5) alkoxy groups and / or 1-3 COOR6 groups, (C1 -C5) alkoxy, (C1-C5) -alkylthio, (C1-C5) -perfluoroalkyl, cyano, nitro, or two substituents together form a group selected from the group consisting of -O- (CH2) pO-, -O- CH2) p-CH2-, -O-CH = CH-, - (CH2) p + 2-, -NH- (CH2) p + 1-, -N (C1-C3-alkyl) - (CH2) p + 1-, and -NH-N = CH-, where p = 1 or 2, and the terminal oxygen atoms and / or carbon atoms and / or nitrogen atoms are attached directly to adjacent ring carbon atoms, NR7R8, where R7 and R8, independently of one another, may be hydrogen, C1-C5-alkyl or (CO) -C1-C5-alkyl (CO) NR11R12, wherein R11 and R12, independently of one another, represent hydrogen or a C1-C5-alkyl group, or a (C1-C5-alkylene) -O- (CO) - (C1-C5) alkyl group, R5 represents a partially or completely fluorinated C1-C3-alkyl group, R6 represents a group selected of: - (C1-C10) -alkyl, which is partially or completely halogenated- (C2-C10) -alkynyl, - (C1-C8) alkyl (C3-C7) cycloalkyl, - (C2-C8) alkenyl (C3- C7) cycloalkyl, - (C1-C8) alkylheterocyclyl, - (C2-C8) -alkenylheterocyclyl, -R9, - (C1-C8) alkyl-R9, - (C2-C8) alkenyl-R9, - (C2-C8) alkynyl-R9, -CH2-S- (C1-C10) -alkyl, -CH2-S-R9, -CH2-SO2-R9, - (CH2) n-R9, -CH2-SO2- (C1-C10) - alkyl, - (CH2) n-CN- (CH2) n-Hal, where Hal represents F, Cl or I-CH2-O- (C1-C10) -alkyl, - (CH2) n-NR7R8 where R7, R8 has the above meaning -CH2-O-R9, where R9 represents aryl which may be optionally substituted by 1-3 alkyl, hydroxy, halogen, cyano or C1-C5-alkoxy groups or a heteroaryl group where the heteroaryl group may contain 1-3 heteroatoms which can be optionally substituted with 1-3 alkyl, hydroxy, halogen, cyano or C1-C5-alkoxy |
| priorityDate | 2006-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.