| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate |
2010-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_def54360ed800244b57e6ba0036985b1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01af72da9802742b2e3e88ca7a94e73d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7f341d72ed69260e056b629835cbcb9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69e0826dbdf6192a2508e71b82c85038
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f16db5b4e55b50e75d0bba592a96794c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1dde80845f0452618affe107f4c4d29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_028e4f3270f9dcfafcac6f9029e2dfd0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77d8e95d24bd4da262b00b40f7f89988
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12713401365b17230953962b63444eac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8debf815d48216deb7e65a6b87668b2 |
| publicationDate |
2010-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
HR-P20100620-T1 |
| titleOfInvention |
CHEMICAL AND SITUATION SULFONING PROCEDURE |
| abstract |
A process for the preparation of a compound of formula IIa: wherein R is a suitable sulfonate ester; from (C1-C6) alkyl-4-piperidinecarboxylate compound according to formula III: which process comprises the following steps: (a) reacting a (C1-C6) alkyl-4-piperidinecarboxylate compound according to formula III with di-tert-butyl dicarbonate in the presence of toluene or xylene forming a first mixture comprising toluene or xylene, tert-butanol and a compound of formula IV: (b) substantially removing tert-butanol from the first mixture; (c) reacting a compound of formula IV with a suitable in situ reducing agent in the presence of toluene or xylene to form a second mixture containing toluene, reducing by-products including alcoholic by-products and a compound of formula V: (d) majority removal of alcoholic by-products -products from another mixture; and (e) reacting a compound of formula V with a suitable in situ sulfonating agent to form a sulfonate ester in the presence of a suitable base and toluene to form a compound of formula IIa. The patent contains 7 more patent claims. |
| priorityDate |
2005-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |