http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HR-P20090341-T1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_30ed587317ad9a18467c0752dea305e6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4858 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-473 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 |
| filingDate | 2009-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21e1d1c833cf1eecd9555dda680401bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fe1bceff4aee5c1c4ed9217ece4f635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a6f141df43ec2ca48236ad8ad0f973a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb66c86939ca2759d9bc3475d12b008b |
| publicationDate | 2009-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HR-P20090341-T1 |
| titleOfInvention | SOFT CAPULOS CONTAINING PALONOSETRON HYDROXYCLORIDE WITH IMPROVED STABILITY AND bioavailability |
| abstract | Soft gelatin capsule for oral administration, comprising: a) a soft gelatin outer shell having an oxygen permeability of less than about 1.0 x 10-3 ml.cm/(cm2.24 hr.atm); teb) a lipophilic liquid internal filling composition comprising: i) more than about 50% by weight of one or more lipophilic ingredients; ii) from about 1 to about 20% by weight of water miscibilized or homogenized in said one or more lipophilic ingredients; iii) from about 0.05 to about 2.0 mg of palonosetron as palonosetron hydrochloride solubilized or dispersed in said water; teiv) a surfactant, said capsule showing pharmacokinetics when taken orally on an empty stomach, which is bioequivalent to a formulation having more than 95% absolute bioavailability, with bioequivalence established with a 90% confidence interval for AUC between 80% and 125%. The patent contains another 26 patent claims. |
| priorityDate | 2006-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.