http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HR-P20080494-T3
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Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5ffa3f9d6b87e15e0a1551fb129b531 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 |
filingDate | 2008-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8efbc1c278630214c1ac6c772cc2fa97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bb948fba2c95f9b558c396067bd1def http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4437a72ed786a78ed657dfbe0229a225 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd525db4083146979e8f26008a0fac15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83695ecba47c2e561d1638f235edafa8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff580bc019545a4fe1930e6b05ad38ce |
publicationDate | 2008-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | HR-P20080494-T3 |
titleOfInvention | 1-Phenylalkanecarboxylic acid derivatives for the treatment of neurodegenerative diseases |
abstract | Compounds of general formula (I): wherein B is a H or alpha amino acid side chain, R and R 1, are the same and represent linear or branched C 1 -C 4 alkyl, or form a ring of 3 to 6 carbon atoms to which they are joined, Ar is phenyl substituted with one or more R3 groups wherein R3 represents: - halogen as previously defined, CF3, C3-C8 cycloalkyl which may be substituted by one or more C1-C4 alkyl and / or oxo groups, CH = CH2, NO2lCH2OH, CN , methylenedioxy, ethylenedioxy, - phenyl which may be substituted by one or more of the following groups: halogen as previously defined, CF3, OCF3, OH, linear or branched C1-C4 alkyl, saturated heterocyclyl of at least 4 carbon atoms with at least 1 heteroatom, C3-C8 cycloalkyl which may be substituted by one or more linear or branched C1-C4 alkyl groups, CF3 and / or OH, -OR4 or NHCOR4 wherein R4 is CF3, linear or branched C2-C6 alkenyl or alkynyl, benzyl, phenyl which may be substituted with one or more slje children groups: halogen as previously defined, CF3, OCF3, OH, linear or branched C1-C4 alkyl, saturated heterocyclyl having at least 4 carbon atoms and at least 1 heteroatom, C3-C8 cycloalkyl which may be substituted by one or more linear or branched C1-C4 alkyl groups, CF3 and / or OH, - SR5, SO2R5 or COR5, where R5 is linear or branched C1-C6 alkyl, or Ar is heterocyclyl selected from the following group: pyrrole, pyrazole, furan, thiophene, indole, isoindole, benzofuran, benzothiophene, imidazole, oxazole, isoxazole, thiazole, benzoimidazole, benzoxazole, benzothiazole, pyrimidine, pyrazine, quinoline, isoquinoline, quinazoline, quinoxaline, dibenzofuran, dibenzo-pyrazine, cinnazine naphthyridine, 1,3-dioxole, 1,3-benzodioxole, and said heterocyclic ring may be substituted with one or more R3 as defined above. The patent contains 10 more patent claims. |
priorityDate | 2004-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 81.