http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HR-P20080493-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_995c71109762882f3cc26e74d8d61acf |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2008-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75e33b286d3c195cf0fdb9a7fa709902 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba5ede92d04fb5a45804b62ed7f8708b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2ccf358c88132a4b059be4684062732 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90fbb4e55c3736c478835e7db95f754a |
| publicationDate | 2009-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HR-P20080493-T3 |
| titleOfInvention | SUBSTITUTED QUINOLINE DERIVATIVES AS MITOTIC CHINESE INHIBITORS |
| abstract | A compound of formula I: wherein: m is an integer from 0 to 3, R 1 is selected from the group consisting of acylamino, carboxyl ester, and C 1 to C 5 alkyl, optionally substituted with hydroxy, or halogen; R 2 is hydrogen or C 1 to C 5 alkyl; R3 is -C (= X) -A, wherein A is selected from the group consisting of aryl, heteroaryl, heterocycle, and cycloalkyl, each of which may be optionally substituted with 1 to 4 substituents selected from the group consisting of C1 to C4 alkyl C1 to C4 alkoxy, halogen, hydroxy, and nitro, and X is oxygen or sulfur; R 4 is -alkylene-heterocycle or -alkylene-NR 7 R 8, wherein alkylene is C 1 to C 4 straight alkylene; R7 and R8 are independently selected from the group consisting of hydrogen, C1 to C4 alkyl, arylalkyl, heteroarylalkyl, cycloalkyl, and cycloalkylalkyl; R5 is selected from the group consisting of L-A1, wherein A1 is selected from the group consisting of aryl, heteroaryl, heterocycle, and cycloalkyl, each of which may be optionally substituted with 1 to 4 substituents selected from the group consisting of C1 to C4 alkyl, C1 to C4 alkoxy, halogen, hydroxy, and nitro, wherein L is selected from the group consisting of oxygen, NR9, wherein R9 is hydrogen or alkyl, -S (O) q-, wherein q is 0, 1 or 2, and C1 to C5 alkylene, optionally substituted with hydroxy, halogen or acylamino; and R6 is selected from the group consisting of C1 to C5 alkyl. C2 to C5 alkenyl, C2 to C5 alkynyl, -CF3, C1 to C5 alkoxy, halogen, and hydroxy; or pharmaceutically acceptable salts or esters thereof. The patent contains another 36 patent claims. |
| priorityDate | 2004-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.