abstract |
A process for the production of a solid pharmaceutical composition which can be administered orally and which contains 5-chloro-N - ({(5S) -2-oxo-3- [4- (3-oxo-4-morpholinyl) -phenyl] -1, 3-Oxazolidin-5-yl} -methyl) -2-thiophenecarboxamide (I) in hydrophilized form, characterized in that (a) the granulation containing the active substance (I) in hydrophilized form is first produced by a wet granulation process, and (b) ) the granulate is then converted into a pharmaceutical composition, optionally with the addition of pharmaceutically acceptable excipients. The patent contains another 19 patent claims. |