http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HR-P20080120-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3d6993da1451c98ccf8893914fc35c4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-14 |
| filingDate | 2008-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e4a2ade51801641d5627ad993ce012c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f8d8414f012b451dff5204d16de28e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32fba48e0aed5dbd4ba5cc0d0474c3f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c89f1b60b50a88531779796b974752c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2cb1924a74793151792f9f4ff92c749 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6388d3c84c7c907c009a29501d5df061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8109c4d0a98e53daceb413bc1b8e03b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fb5700af2dd2532f709b0d395f0fe31 |
| publicationDate | 2008-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HR-P20080120-T3 |
| titleOfInvention | COMPOUNDS AND PROCEDURES FOR INHIBITION OF MYTHOSE PROMOTION WITH THE AUROR KINASE INHIBITION |
| abstract | A compound of formula (A): or a pharmaceutically acceptable salt thereof, wherein: Rf1 is hydrogen or Rf1 and Rf2 together form a bond; Rf2 is hydrogen or Rf2 forms a bond with Rf1 or Rx; Rx and Ry independently of one another are hydrogen, fluorine or an optionally substituted C1-6 aliphatic group, or Rx and Ry together with the carbon atom to which they are attached form an optionally substituted tri- to a six-membered cycloaliphatic ring; or Rx and Rf2 together form a bond; if Rf1 is hydrogen then G is hydrogen, optionally substituted aliphatic group or ring B, if Rf1 and Rf2 together form a bond, then G is hydrogen, -OR5, -N (R4) 2, -SR5, optionally substituted aliphatic group or ring B; ring A is a substituted or unsubstituted five- or six-membered aryl, heteroaryl, cycloaliphatic or heterocyclic ring; ring B is a substituted or unsubstituted aryl, heteroaryl, heterocyclic or cycloaliphatic ring; ring C is a substituted or unsubstituted aryl, heteroaryl, heterocyclic or cycloaliphatic ring; R a is hydrogen, -C (O) R 1, -CO 2 R 1, -SO 2 R 1 or a C 1-3 aliphatic group containing from 0 to 2 substituents independently selected from R 3 or R 7; R e is hydrogen, -OR 5, -N (R 4) 2, - SR5, -NR4C (O) R5, -NR4C (O) N (R4) 2, -NR4CO2R6, -N (R4) SO2R6, -N (R4) SO2N (R4) 2, or a C1-3 aliphatic group optionally substituted by R3 or R7; R1 is a C1-6 aliphatic group or an optionally substituted aryl, heteroaryl or heterocyclic group; each R3 is independently selected from the group consisting of: -halogen, -OH, -O (C1-3 alkyl), -CN, -N (R4) 2, -C (O) (C1-3 alkyl), -CO2H. -CO2 (C1-3 alkyl), -C (O) NH2 and -C (O) NH (C1-3 alkyl); each R4 independently is hydrogen or an optionally substituted aliphatic group, aryl, heteroaryl or heterocyclic group; or two R4 bonded to the same nitrogen atom, together with that nitrogen atom, form an optionally substituted five to six membered heteroaryl or four to eight membered heterocyclic, in addition to said nitrogen atom, it further comprises in the ring 0-2 heteroatoms selected from N, O and S; each R 5 is independently hydrogen or an optionally substituted aliphatic, aryl, heteroaryl or heterocyclic group; each R 6 is independently an optionally substituted aliphatic or aryl group; each R 7 is independently an optionally substituted aryl, heterocyclic or heteroaryl group. The patent contains 55 more claims. |
| priorityDate | 2004-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.