| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef9b262e05836a02d9ef203f65e7131b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 |
| filingDate |
2004-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7eb235e5060925f6a03abd46b3a4599
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12cb9d0ab3bdecbc7518458f3fc9dcdd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f29af81f92d7a2d22e80bf2ab4e626d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce567db622f25d4cc089e5e393fee34e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b300854350220a9b1e442c9860d9359 |
| publicationDate |
2013-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
HR-P20041198-B1 |
| titleOfInvention |
PHARMACEUTICAL PREPARATIONS CONTAINING STABILIZED AMORPHIC FORM OF DONEPESIL HYDROCHLORIDE |
| abstract |
The present invention relates to stabilized pharmaceutical compositions with an amorphous form comprising 1-benzyl-4 - ((5,6-dimethoxy-1-indanone) -2-yl) methyl-piperidine (donepezil) hydrochloride and to a process for stabilizing this compound. The pharmaceutical composition is prepared in situ by forming donepezil hydrochloride and applying the resulting solution to a mixture of pharmaceutically acceptable excipients. The amorphous form of donepezil hydrochloride is stabilized by the addition of a crystallization inhibitor to a solution or mixture of a pharmaceutically acceptable excipient. |
| priorityDate |
2002-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |