| abstract |
<IMAGE NAME = "20040549_01" TYPE = "jpg" CENTER = TRUE /> The present invention relates to compounds of general formula (I), wherein: X represents a hydrogen or halogen atom; R <SUB> 1 </SUB> represents a hydrogen atom or an (C <SUB> 1 </SUB> -C <SUB> 4 </SUB>) alkyl group; R <SUB> 2 </SUB> and R <SUB> 3 </SUB> represent, independently of one another, a hydrogen atom or (C <SUB> 1 </SUB> -C <SUB> 4 </SUB> ) an alkyl group, or R <SUB> 2 </SUB> and R <SUB> 3 </SUB> form, together with the nitrogen atom to which they are attached, a pyrrolidinyl, piperidinyl, mophrolinyl or 4-alkylpiperazinyl group; and Het represents a heteroaromatic group of the type pyridinyl, 1-oxidopyridinyl, quinolinyl, isoquinolinyl, pyrimidinyl, pyrazinyl, pyridazinyl, wherein the heteroaromatic group may contain one or more halogen atoms and / or one or more (C <SUB> 1 </SUB> - C <SUB> 4 </SUB>) alkyl or (C <SUB> 1 </SUB> -C <SUB> 4 </SUB>) alkoxyl groups; in the form of bases, acid addition salts, solvates or hydrates. The invention also relates to pharmaceutical compositions containing them, to processes for their preparation, as well as to the synthesis of intermediates. |