http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HR-P20030889-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 |
| filingDate | 2003-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27a45fc27833fc3aa95f1e00a50a75c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4adcd31e3b2ff98f8bcc39b8eb11755a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e6de93399b16fca8512d7b71b40edec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ac7eacba374807feab484feb085af25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61b7fd4bbec84335debed33adb09590f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0df7171bbca573d8e7158b4760c1d55d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_500c119a1159d40f3e2bb161feba719c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcdd1f1b419b833bf05999d8f6dc08a2 |
| publicationDate | 2011-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HR-P20030889-B1 |
| titleOfInvention | CARBOXYLIC ACID SUBSTITUTED OXAZOLE DERIVATIVES IN APPLICATION AS PPAR-ALPHA AND -GAMA ACTIVATORS IN THE TREATMENT OF DIABETES |
| abstract | Compounds selected from the group of compounds represented by formula I: wherein R 1 represents aryl or heteroaryl; R 2, R 3, R 4 and R 6 are independently hydrogen, hydroxy, C 2-8 alkenyl, halogen, C 1-7 alkyl or C 1-7 alkoxy, in which at least one of R 2, R 3, R 4 and R 6 does not represent hydrogen, or R 3 and R 4 are bonded together to form a ring together with the carbon atom to which they are bonded, and R 3 and R 4 together represent -CH = CH-S-, -S-CH = CH-, -CH = CH-O-, -O-CH = CH-, -CH = CH-CH = CH-, - (CH2) 3-5-, -O- (CH2) 2-3- or - (CH2) 2-3-O- and where R2 and R6 are as defined above; R5 represents C1-7-alkoxy, C2-5-alkenyloxy, R7 represents hydrogen or C1-7-alkyl; R8 represents hydrogen or C1-7-alkyl; R9 represents hydrogen or C1-7-alkyl; R10 represents aryl; n is 1, 2 or 3; wherein the bond between the carbon atom Ca and the carbon atom Cb represents a carbon carbon single or double bond; and pharmaceutically acceptable salts and esters thereof; wherein: "aryl" is a phenyl or naphthyl group which may be optionally mono- or polysubstituted by halogen, hydroxy, CN, CF3, NO2, NH2, N (H, C1-7-alkyl), N (C1-7-alkyl) ) 2, carboxy, aminocarbonyl, C1-7-alkyl, C1-7alkoxy, phenyl and / or phenyloxy; "heteroaryl" is an aromatic 5- or 6-membered ring which may contain 1, 2 or 3 atoms selected from a nitrogen, oxygen and / or sulfur or bicyclic aromatic group containing two 5- or 6-membered rings, in which one or both rings may contain 1, 2 or 3 atoms selected from nitrogen, oxygen or sulfur, which heteroaryl group may be optionally mono- or polysubstituted by halogen, hydroxy, CN, CF3, NO2, NH2, N (H, C1-7-alkyl) , N (C1-7-alkyl) 2, carboxy, aminocarbonyl, C1-7-alkyl, C1-7-alkoxy, phenyl and / or phenyloxy; alkyl or C1-7-alkyl groups may be substituted by halogen, hydroxy, C1-7-alkoxy, C1-7-alkoxy-carbonyl, NH2, N (H, C1-7-alkyl) and / or N (C1-7) -alkyl) 2. The patent contains 21 more patent claims. |
| priorityDate | 2001-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.