http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HR-P20030448-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1542e8802a0e6a7a8a7c6bd5627eb857 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-82 |
| filingDate | 2003-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a01be08511d1b9024a08ddac7a6dd5d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bc97a3ab1a05a58ba7f8a606ac65930 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a48d4278aefdf18d96f720a0b7222cfd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2f20b668b9e09ea82c52fc8212a9803 |
| publicationDate | 2006-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HR-P20030448-B1 |
| titleOfInvention | Ortho-substituted nitrogen-containing bisaryl compounds used as potassium channel inhibitors |
| abstract | A compound of formula I, wherein A1, A2, A3, A4, A5, A6, A7 and A8 independently of one another represent nitrogen, CH and CR (5), wherein at least one of these groups represents nitrogen and at least 4 of these groups represent nitrogen. CH; R (1) is C (O) OR (9), SO2R (10), COR (11), C (O) NR (12) R (13) or C (S) NR (12) R (13); R (9), R (10), R (11) and R (12) independently of one another are CxH2x-R (14); x is 0, 1, 2, 3 or 4, where x cannot be 0 if R (14) is OR (15) or SO2Me; R (14) is alkyl having 1, 2, 3, 4, 5 or 6 atoms, cycloalkyl having 3, 4, 5, 6, 7, 8, 9, 10 or 11 carbon atoms, CF3, C2F5, C3F7, CH2F, CHF2, OR (15), SO2Me, phenyl, naphthyl, biphenylyl, furyl, thienyl or an N-containing heteroaromatic having 1, 2, 3, 4, 5, 6, 7, 8 or 9 carbon atoms, phenyl, naphthyl, biphenylyl, furyl, thienyl or heteroaromatic containing N are unsubstituted or substituted by 1, 2 or 3 substituents selected from the group consisting of F, Cl, Br, J, CF3, OCF3, NO2, CN, COOMe, CONH2 , COMe, NH2, OH, alkyl having 1, 2, 3 or 4 carbon atoms, alkoxy having 1, 2, 3 or 4 carbon atoms, dimethylamino, sulfamoyl, methylsulfonyl and methylsulfonyl-amino; R (15) is alkyl having 1, 2, 3, 4 or 5 carbon atoms, cycloalkyl having 3, 4, 5 or 6 carbon atoms, CF3 or phenyl, which is unsubstituted or substituted by 1, 2 or 3 substituents selected from the group consisting of F, Cl, Br, J, CF3, NO2, CN, COOMe, CONH2, COMe, NH2, OH, alkyl having 1, 2, 3 or 4 carbon atoms, alkoxy having 1, 2, 3 or 4 carbon atoms, dimethylamino, sulfamoyl, methylsulfonyl and methylsulfonylamino; R (13) is hydrogen, alkyl having 1, 2, 3 or 4 carbon atoms or CF 3 R (2) is hydrogen, alkyl having 1, 2, 3 or 4 carbon atoms or CF 3; R (3) is CyH2y-R (16); y is 0, 1, 2, 3 or 4, where y cannot be 0 if R (16) is OR (17) or SO2Me; R (16) is alkyl having 1, 2, 3, 4, 5 or 6 carbon atoms, cycloalkyl having 3, 4, 5, 6, 7, 8, 9, 10 or 11 carbon atoms, CF3, C2F5, C3F7 , CH2F, CHF2, OR (17), SO2Me, phenyl, naphthyl, furyl, thienyl or a N-containing heteroamate having 1, 2, 3, 4, 5, 6, 7, 8 or 9 carbon atoms, wherein the phenyl , N-containing naphthyl, furyl, thienyl or heteroaromatic are unsubstituted or substituted with 1, 2 or 3 substituents selected from below, consisting of F, Cl, Br, J, CF3, OCF3, NO2, CN, COOMe, CONH2, COMe, NH2 , OH, alkyl having 1, 2, 3 or 4 carbon atoms, alkoxy having 1, 2, 3 or 4 carbon atoms, dimethylamino, sulfamoyl, methylsulfonyl and methylsulfonylamino; R (17) is hydrogen, alkyl having 1, 2, 3, 4 or 5 carbon atoms, cycloalkyl having 3, 4, 5 or 6 carbon atoms, CF3, phenyl, 2-, 3- or 4-pyridyl, at wherein the phenyl or 2-, 3- or 4-pyridyl is unsubstituted or substituted with 1, 2 or 3 substituents selected from the group consisting of F, Cl, Br, J, CF3, OCF3, NO2, CN, COOMe, CONH2, COMe , NH2, OH, alkyl having 1, 2, 3 or 4 carbon atoms, alkoxy having 1, 2, 3 or 4 carbon atoms, dimethylamino, sulfamoyl, methylsulfonyl and methylsulfonyl-amino; or R (3) is CHR (18) R (19) |
| priorityDate | 2000-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 56.