http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HR-P20000886-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-14 |
| filingDate | 2000-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6354605119c19c00aee83ec4fc7c599b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fa5bf94441cc513c29c9c3022d87c63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa6d2f9feb352140a4cd46a717005248 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_198402f3e4a0467c89762ed3a9e9a1a6 |
| publicationDate | 2008-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HR-P20000886-B1 |
| titleOfInvention | PIROLO [2,3-D] PYRIMIDINE COMPOUNDS |
| abstract | A compound of the formula or a pharmaceutically acceptable salt thereof, wherein R 1 represents a group of the formula wherein the dashed line represents optional double bonds; m is 0, 1, 2 or 3; n is 0, 1, 2 or 3; X, B and D are, each independently, oxygen, S (O) d, wherein d is 0, 1 or 2, NR6 or CR7R8, A and E are, each, CR7R8; aR6 is selected from the group consisting of hydrogen, (C1-C6) alkyl, trifluoromethyl, trifluoromethyl (C1-C6) alkyl, (C1-C6) alkyl (difluoromethylene), (C1-C3) alkyl (difluoromethylene) (C1-C3) alkyl, (C1-C6) alkoxy (C1-C6) acyl, (C1-C6) alkylamino (C1-C6) acyl, (C1-C6) alkyl) 2amino (C1-C6) acyl, (C6-C10) aryl , (C5-C9) heteroaryl, (C6-C10) aryl (C1-C6) alkyl, (C5-C9) heteroaryl (C1-C6) alkyl, (C6-C10) aryl (C6-C10) aryl, (C6- C10) aryl (C6-C10) aryl (C1-C6) alkyl, (C3-C6) cycloalkyl, (C3-C6) cycloalkyl, (C1-C6) alkyl, hydroxy (C2-C6) alkyl, (C1-C6) acyloxy (C2-C6) alkyl, (C1-C6) alkoxy (C2-C6) alkyl, piperazinyl (C1-C6) alkyl, (C1-C6) acylamino (C1-C6) alkyl, (C6-C10) aryl (C1- C6) alkoxy (C1-C6) alkyl, (C5-C9) heteroaryl (C1-C6) alkoxy (C1-C6) alkyl, (C1-C6) alkylthio (C1-C6) alkyl, (C6-C10) arylthio (C1 -C6) alkyl, (C1-C6) alkylsulfinyl (C1-C6) alkyl, (C6-C10) arylsulfinyl (C1-C6) alkyl, (C1-C6) alkylsulfonyl, (C1-C6) alkyl, (C6-C10) arylsulfonyl (C1-C6) alkyl, amino (C1-C6) alkyl, (C1-C6) alkylamino, (C1-C6) alkyl, (C1-C6) alkyl) 2amino (C1-C6) alkyl, R13CO (C1-C6) alkyl, wherein R13 is R20O or R20R21N, wherein R20 and R21 are each independently selected from the group consisting of hydrogen, (C1-C6) alkyl, (C6-C10) aryl (C1-C6) alkyl or (C5-C9) heteroaryl (C1-C6) alkyl; or R14 (C2-C6) alkyl, wherein R14 is (C1-C6) acylpiperazino, (C6-C10) arylpiperazino, (C5-C9) heteroarylpiperazino, (C1-C6) alkylpiperazino, (C6-C10) aryl (C1-C6) ) alkylpiperazino, (C5-C9) heteroaryl (C1-C6) alkylpiperazino, morpholino, thiomorpholino, piperidino, pyrrolidino, piperidyl, (C1-C6) alkylpiperidyl, (C6-C10) arylpiperidyl, (C5-C9) heteroarylpi C10) aryl (C1-C6) alkylpiperidyl, (C5-C9) heteroaryl (C1-C6) alkylpiperidyl, (C1-C6) alkoxyacyl, (C1-C6) alkylaminoaryl, (C1-C6) alkyl) 2aminoacyl or (C1- C6) acylpiperidinyl; R7 and R8 are each independently selected from the group consisting of hydrogen, deuterium, (C1-C6) alkyl, amino, hydroxy, (C1-C6) alkoxy, (C1-C6) alkylamino, (C1-C6) alkyl) amino, (C1-C6) acylamino, (C1-C6) acyl (C1-C6) alkylamino, carboxy, (C1-C6) alkoxyacyl, (C1-C6) alkylaminoacyl, (C1-C6) alkyl) 2aminoacyl, aminoacyl, trifluoromethyl, trifluoromethyl (C1-C6) alkyl, (C1-C6) alkyl (difluoromethylene), (C1-C3) alkyl (difluoromethylene) (C1-C3) alkyl, (C6-C10) aryl, (C5-C9) heteroaryl, (C6-C10) aryl (C1-C6) alkyl, (C5-C9) heteroaryl (C1-C6) alkyl, (C6-C10) aryl (C6-C10) aryl, (C6-C10) aryl (C6-C10) aryl (C1-C6) alkyl, (C3-C6) cycloalkyl, (C3-C6) cycloalkyl (C1-C6) alkyl, hydroxy (C1-C6) alkyl, (C1-C6) acyloxy (C1-C6) alkyl, ( C1-C6) alkoxy (C1-C6) alkyl, piperazinyl (C1-C6) alkyl, (C1-C6) acylamino (C1-C6) alkyl, piperidyl, (C1-C6) alkylpiperidyl, (C6-C10) aryl (C1 -C6) alkoxy (C1-C6) alkyl, (C5-C9) heteroaryl (C1-C6) alkoxy (C1-C6) alkyl, (C1-C6) alkylthio (C1-C6) alkyl, (C6-C10) arylthio ( C1-C6) alkyl, (C1-C6) alkylsulfinyl, (C1-C6) alkyl, (C6-C10) arylsulfinyl (C1-C6) alkyl,, (C1- C6) alkylsulfonyl (C1-C6) al |
| priorityDate | 1998-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.