http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HR-P20000741-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-12 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D521-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 |
| filingDate | 2000-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd353bc9b009350567061c9d0ce4b4a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d25f03fddfa0abe9f6c06598526ca079 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_571d790e60f8c52da323e4d6997ae3f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d411a6a06c8dec7de1e15cebd074c27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db5085f8e62f84f67f096fef710df46b |
| publicationDate | 2009-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HR-P20000741-B1 |
| titleOfInvention | IN WATER SOLUBLE AZOLS AS WIDE SPECTRUM ANTIFUNGALS |
| abstract | Compounds of formula (I) having the formula N-oxides thereof, pharmaceutically acceptable addition salts and stereochemically isomeric forms thereof, wherein L represents a radical of formula wherein each Alk independently represents C1-6-alkanediyl optionally substituted by hydroxy or C1-4- alkyloxy; each n is independently 1, 2 or 3; Y is 0, S or NR2: each R1 independently represents hydrogen, aryl, Het1, or C1-6-alkyl optionally substituted with one, two or three substituents, each of which is independently selected from the group consisting of halogen, hydroxy, mercapto , C1-4-alkyloxy, C1-4-alkylthio, aryloxy, arylthio, aryl-C1-4-alkyloxy, aryl-C1-4-alkylthio, cyano, amino, mono- or di (C1-4-alkyl) amino, mono- or di (aryl) amino, mono- or di (aryl-C1-4-alkyl) amino, C1-4-alkyloxycarbonylamino, benzyloxycarbonylamino, aminocarbonyl, carboxyl, C1-4-alkyloxycarbonyl, guanidinyl, aryl or Het2; each R2 independently represents hydrogen or C1-6-alkyl; or in the event that R 1 and R 2 touch the same nitrogen atom, they may be taken together to form a heterocyclic radical selected from the group consisting of morpholinyl, pyrrolidinyl, piperidinyl, homopiperidinyl or piperazinyl, said heterocyclic radical being optionally substituted with a substituent selected from a group consisting of C1-4-alkyl, aryl, Het2, aryl-C1-4-alkyl, Het2-C1-4-alkyl, hydroxy-C1-4-alkyl, amino, mono- or di (C1-4-alkyl) amino, amino-C1-4-alkyl, mono- or di (C1-4-alkyl) amino-C1-4-alkyl, carboxyl, aminocarbonyl, C1-4-alkyloxycarbonyl, C1-4-alkyl-oxycarbonylamino or mono- or di (C1-4-alkyl) aminocarbonyl; or they may be taken together to form an azido radical; each R 3 independently represents hydrogen, hydroxy or C 1-4 alkyloxy; aryl is phenyl, naphthalenyl, 1,2,3,4-tetrahydro-naphthalenyl, indenyl or indanyl; each of said aryl groups may be optionally substituted with one or more substituents selected from the group consisting of halogen, C1-4-alkyl, hydroxy, C1-4-alkyloxy, nitro, amino, trifluoromethyl, hydroxy-C1-4-alkyl , C1-4-alkyloxy-C1-4-alkyl, amino-C1-4-alkyl, mono- or di (C1-4-alkyl) amino-C1-4-alkyl; Het1 represents a monocyclic or bicyclic heterocyclic radical; wherein said monocyclic heterocycle is selected from the group consisting of pyridinyl, piperidinyl, homopiperidinyl, pyrazinyl, pyrimidinyl, pyridazinyl, triazinyl, triazolyl, pyranyl, tetrahydropyranyl, imidazolyl, imidazolinyl, imidazolidinyl, pyrazinyl, pyrazinyl , oxazolidinyl, isoxazolyl, pyrrolyl, pyrrolinyl, pyrrolidinyl, furanyl, tetrahydrofuranyl, thienyl, thiolanyl, dioxolanyl; wherein said bicyclic heterocyclic radical is selected from the group consisting of quinolinyl, 1,2,3,4-tetrahydro-quinolinyl, isoquinolinyl, quinoxalinyl, quinazolinyl, phthalazinyl, cinnolinyl, chromanyl, thiochromanyl, 2H-chromenyl, 1,4-benzo- dioxanyl, indolyl, isoindolyl, indolinyl, indazolyl, purinyl, pyrrolopyridinyl, furanopyridinyl, thienopyridinyl, benzothi |
| priorityDate | 1998-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 68.