http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GR-990100386-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7e4de608e00ae4c35e3421e0ade664ef |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 1999-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b79325363fd12d068af9a076fa95bcfe |
| publicationDate | 2001-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GR-990100386-A |
| titleOfInvention | A OR B (MONO- OR DI-ALKYLAMINOMETHYL)-C-BUTYROLACTONES AND THEIR CORRESPONDING TETRAHYDROFURAN ANALOGUES AS NEW PROTOTYPE NOOTROPES, ANTI-ANOIC (ALZHEIMER'S DISEASE), ANTIPELIPUS AND NEUROPROTECTIVE DRUGS WITH A UNIQUE MEDICATION OF ... . |
| abstract | The invention relates to the α or β- (Mono- or di-alkylaminomethyl) -g-butyrolactones, their tetrahydrofuran analogs and their pharmaceutically acceptable stationary salts, products prepared according to the methodology described in U.S. Pat. 960100061 / 21-2-1996 (GR), PCT Int.Appl. WO 9730983, i.e., conversion of the oxofuran carboxylic acids to the corresponding acid chlorides and to N-mono, or N, N-dialkylamides reduced to aminodiols which give the final products by cyclization under appropriate conditions. M1 selective muscarinic agonists and / or M2 antagonists of cholinergic receptors, which also have inhibitory control over sodium ion channels, are suggested as anti-depressant and anti-dementia (especially Alzheimer's disease) drugs, as anti-inflammatory drugs. optic and nerve protectors (especially some low-endogenous muscarinic agonists that have inhibitory control of sodium channels, anti-NMDA action and / or selective serotonergic activation at the base of the brain) with potentiation of memory and psychotic, as non-opioid analgesics, as antidepressants and as enhancers / stabilizers of the action of clinically used antidepressants.ΰ |
| priorityDate | 1999-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.