http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GR-35018-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/F16L9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/F16L9-10 |
| filingDate | 1967-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1968-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GR-35018-B |
| titleOfInvention | METHOD FOR THE PREPARATION OF SULPHONAMIDS. |
| abstract | method for the preparation of sulfonylurea derivatives of the general formula:n[*]nin which R means hydrogen or methyl, R1 hydrogen, R2 a hydroxy group and R1 and R2 together the oxygen atom of a ketone group, which may also be in the form of a ketal, R3 phenyl, which may be substituted by the following - alkyl-, lower - alkoxy-, lower alkylthio-, amino-, acetyl-, halogen-, acylamino-, diacylimido - groups or by alkoxy- and/or halogen-substituted benzamidoethyl or a 5-6-membered N-linked nitrogen heterocyclic ring, characterized by thatna. react a reactive derivative of a corresponding sulfonylcarbamic acid of general formula II:nR3 - SO2 - NH - COOHnor a sulfonyl isocyanate of general formula III:nR3 - SO2 - NCOnafter a compound of the general formula:n[*]nin which R, R1 and R2 have been given the meaning,nor thatnb. react in an amide salt of a sulfonic acid of the general formula V:nR3 - SO3Hnafter an isocyanate compound of the general formula:n[*]nin which R has the meaning given, or after a corresponding ketalnor thatnc. we treat with alkali a compound of the general formula:n[*]nand we reduce, if desired, one to the reaction product obtained according to a) or b) if a ketone group was present on the ring and we separate the unwanted isomers obtained there, oxidize, if desired, a hydroxy group in the reaction product, or saponify, if desired, a resulting ketal. |
| priorityDate | 1966-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.