| abstract |
This patent discloses a method for the analysis of 4- [4- (dimethylamino) -1 - (4`-fluorophenyl) -1-hydroxybutyl] -3- (hydroxymethyl) -benzonitrile as a racemic or non-racemic mixture of enantiomers isolated of the enantiomers, said method comprising the step of crystallizing fractional 4- [4- (dimethylamino) -1- (4`-fluorophenyl) -1-hydroxybutyl] -3- (hydroxymethyl) -benzonitrile as one salt with (+) - (S, S) - or (-) - (II, R) -E enantiomer of O, C- -di-p-toluene tartaric acid in a solvent system comprising 1-propanol, ethanol or acetonitrile. |