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filingDate 1996-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97d8f76bb71180cd3af44e10eaa69f0f
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publicationDate 1999-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GE-P19991873-B
titleOfInvention Paclitaxel Synthesis from Precursor Compounds and Methods of Producing the Same
abstract Simplification of chemical processes, reduction of the cost of the final product. 2. Essence Semi-synthesis of paclitaxel by esterifying 3-phenylisoserine acids (having hydrogenatable benzyl protecting groups at C-2 position) to produce C-13 hydroxyl of 7-0-protected baccatin III. Utilizes triethylsilyl (TES) protection at the C-7 position. 3. Field of application Medicine, in particular chemotherapy. 2 ind.cl., and 8 dep. cl.
priorityDate 1995-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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