http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-997666-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59e1d955a7b1560dc68cf7fd800e8fac |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B31-185 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B31-18 |
| filingDate | 1961-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83fb3ed293ab3ba7c435577347773ec2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d1815c3a1fda7e093d1e92043eacc85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8e0138fa7250b972f76fff58204df65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8a7e60d9f69777ec2db7b0bbef9f1d5 |
| publicationDate | 1965-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-997666-A |
| titleOfInvention | Sulphation of reduced product of oxidised starch and its methyl ester |
| abstract | The sulphate of the reduced product of oxidized starch is made by oxidising starch so as to convert the primary alcoholic groups therein to carboxyl groups, reducing the simultaneously formed keto-groups back to secondary alcoholic groups, and sulphating the resultant reduced product. Oxidation and reduction may be effected by known procedures using e.g. nitric acid, or nitrogen dioxide for oxidation, and sodium borohydride, sodium amalgam, or hydrogen in presence of a catalyst for reduction. The product of the reduction step may be esterified to form the methyl ester, which is then sulphated. The sulphation may be effected by reaction with chlorosulphonic acid in absence of a solvent, or in presence of a solvent such as formamide, dimethyl formamide, acelamide or pyridine. The sulphated product may be converted to an alkali metal salt by reaction with alkali. The sulphated product, or its alkali salt may be isolated by precipitation in ethanol, and purified by dialysis or fractional precipitation. The product is thought to contain units of glucuronic acid, 2- or 3-sulphated glucuronic acid, and 6-sulphated glucose. Aqueous solutions of the product have blood-anticoagulant activity, cholesterol-reducing activity, and lipaemia cleaning activity (see Division A5).ALSO:Injectable aqueous solutions having blood anti-coagulant activity, cholesterol-reducing activity and lipaemia cleaning activity contain the sulphate of the reduction product of oxidized starch, or methyl esters or alkali salts thereof. The sulphate is made by oxidizing starch so as to convert the primary alcoholic groups therein to carboxyl groups, reducing the simultaneously formed keto-groups back to secondary alcoholic groups, and sulphating the resultant reduced product (see Division C3). |
| priorityDate | 1961-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.