http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-996704-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59e1d955a7b1560dc68cf7fd800e8fac |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J43-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 |
| filingDate | 1961-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1965-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-996704-A |
| titleOfInvention | New steroidthiazole compounds and process for the production thereof |
| abstract | The invention comprises steroid-thiazoles of the general formula <FORM:0996704/C2/1> wherein R1 represents two hydrogen atoms or an oxygen atom, R2 represents a hydrogen atom or a hydroxy radical, R3 represents a hydrogen atom or an alkyl radical, and R4 represents an alkyl, cycloalkyl or phenyl radical or a phenyl radical substituted by one or more alkoxy, halogen or alkyl substituents, and the preparation thereof by reacting steroid compounds of the general formula <FORM:0996704/C2/2> wherein X represents a halogen or -OSO2CH3 and R1 and R2 have the above significance, with a substituted thiourea of the general formula <FORM:0996704/C2/3> wherein R3 and R4 have the above significance. The invention also includes a process for reducing steroid-thiazoles of the first general formula above wherein R1 represents two hydrogen atoms with an alkali metal complex hydride to form steroid-thiazoles of the general formula <FORM:0996704/C2/4> wherein R3 and R4 have the above significance' and a process for the preparation of steroids of the general formula <FORM:0996704/C2/5> wherein Z represents an oxygen atom or <FORM:0996704/C2/6> , R4 has the above significance and R5 represents a hydrogen atom or -COCH2CH2COOH, but when Z is an oxygen atom R5 always represents -COCH2CH2COOH, by reacting steroids of the general formula <FORM:0996704/C2/7> wherein Y represents an oxygen atom or <FORM:0996704/C2/8> and R4 has the above significance. |
| priorityDate | 1960-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 17.