http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-996309-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f24f7c8a897a001de145bd2b572a4bc |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-568 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-569 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-568 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 |
| filingDate | 1962-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1965-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-996309-A |
| titleOfInvention | New 19-nor steroids |
| abstract | The invention comprises steroids of the formula <FORM:0996309/C2/1> (wherein R1 is OH or Oacyl, R2 is hydrogen or a saturated or unsaturated hydrocarbon radical of at most 4 carbon atoms, or R1 and R2 together constitute a keto group; and X is a halogen atom or the group Y-SO3 in which Y is an aliphatic, aromatic or araliphatic hydrocarbon radical which may be alkyl, nitro or halogen substituted) and their preparation by halogenating or sulphonylating a D 5-3,17- dihydroxy - 19 - nor - androstene 17 - acylate and, when required, oxidizing the product (after saponification when required) to the 17-ketone, or reacting it with a hydrocarbon metal compound to give the 17b -hydroxy-17a -hydrocarbon compound which may then be acylated. Halogenation may be effected with a thionyl halide or a phosphorus halide and sulphonylation with a sulphonic acid or functional derivative thereof. 17a -alkynyl compounds may be reduced to the corresponding 17a -alkenyl and -alkyl compounds. Examples are given. The steroids of the invention, which are stated to have progestative, androgenic, anabolic, uterotrophic and gonad-inhibiting properties, may be made up into pharmaceutical compositions with inert carriers. |
| priorityDate | 1961-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.