http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-992738-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bf2ba08adb8ed810fa2aafc13dea308 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-16 |
| filingDate | 1963-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1965-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-992738-A |
| titleOfInvention | New sulphoxides |
| abstract | The invention comprises ribonucleosides containing in the 51-position a sulphoxide residue R-SO-, in which R is an unsaturated or saturated alkyl radical or an aralkyl or cycloalkyl radical and the preparation thereof by reacting a 51-desoxy-51-R-thio-ether of a ribonucleoside with an appropriate oxidizing agent for the conversion of a sulphur atom of a thio-ether group into a sulphoxide residue or by reacting a 51-desoxy-51-R-thio-ether of D-ribose or D-desoxyribose with an agent for converting the sulphide into its sulphoxide and reacting the sulphoxide so obtained with an appropriate purine or pyrimidine. Allyl-(adenosyl-51)-sulphide is prepared by reacting allyl mercaptan with 51-desoxy-51-tosyl-21,31-isopropylidene adenosine to give 51-desoxy-51-allylthio-21,31-isopropyliden adenosine and hydrolysing the ketal. Similarly are prepared propyl-iso-propyl- and benzyl-(adenosyl-5)-sulphides. |
| priorityDate | 1962-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.