http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-989033-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_364b3cbf956b10ca710b6407d25b6fd0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-29 |
| filingDate | 1962-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77e733ce5de70fcb4e656fb73d050d8c |
| publicationDate | 1965-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-989033-A |
| titleOfInvention | N-substituted-1-phenyl-2-aminoalkanes |
| abstract | The invention comprises compounds of the formula <FORM:0989033/C2/1> (wherein R represents an alkyl group of not more than 4 carbon atoms and R1 and R2 each represent a phenyl or an alkyl substituted phenyl group, the alkyl group having not more than 4 carbon atoms); and a process for the preparation of compounds of the formula <FORM:0989033/C2/2> (wherein X and X1 each represent a hydrogen atom or together represent a single bond between the carbon atoms to which they are attached) in which a 1-phenyl-2-aminoalkane is reacted with an aldehyde of the formula <FORM:0989033/C2/3> and the azomethine bond of the resulting compound of the formula <FORM:0989033/C2/4> is reduced to give a compound of the Formula II wherein X and X1 represent a double bond which may be optionally reduced to give a compound of the Formula II wherein X and X1 represent hydrogen atoms. The azomethine bond is preferably reduced with sodium-borohydride and the double bond, when present in compounds of the Formula II with hydrogen and Raney nickel. Aldehydes of the Formula III may be prepared by reaction of a ketone of the formula R1-CO-R2 with acetylene in the presence of a condensing agent to give an acetylenic alcohol of the formula <FORM:0989033/C2/5> which is isomerized to the desired aldehyde by treatment with an acid. |
| priorityDate | 1962-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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