http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-984704-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56666880a5e2b7703e98a4f9b2d9daf6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-30 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-30 |
filingDate | 1962-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1965-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-984704-A |
titleOfInvention | Hydrazone derivatives |
abstract | The invention comprises compounds of the general formula <FORM:0984704/C2/1> and their pharmaceutically acceptable non-toxic acid addition (including ascorbic acid) and quaternary ammonium salts wherein X is a hydrogen or a halogen atom or a methyl, methoxy or trifluoromethyl radical; X1 is a hydrogen or halogen atom; m is 0 or 1; n is 1 or 2; R is a phenyl, tolyl, halophenyl, hydroxyphenyl, alkanoyloxyphenyl, mono-, di- or tri - methoxyphenyl, methylenedioxyphenyl, diethylaminoethoxyphenyl, alkanamidophenyl, dialkylaminophenyl, nitrophenyl, cyanophenyl, carboxyphenyl, naphthyl, anthryl, phenethyl, styryl, benzyl, alkyl, cyclohexyl, cyclohexenyl, benzhydryl, pyridyl, methylpyridyl, indolyl quinolyl, thienyl, furyl, nitrofuryl, dihydropyranyl, or dimethylphenylpyrrolyl, radical R1 is a hydrogen atom or a methyl or phenyl radical or R and R1 are combined so that the radical = CRR1 is a cyclohexylidene, 4-methyl-4-azacyclohexylidene or fluorenylidene radical. The compounds may be prepared by reacting a compound of the general formula <FORM:0984704/C2/2> with a compound RR1C = Z wherein C = Z is a carbonyl radical or a radical equivalent thereto for reaction with a hydrazine to form a hydrazone thereof. The 1 - diphenylalkyl - 4 - amino - piperazines and - homopiperazines used as starting materials are prepared by reacting a diphenyl alkyl halide with nitrosopiperazine or nitrosohomopiperazine or with piperazine or homopiperazine with subsequent nitrosation to give a 1 - diphenylalkyl - 4 - nitroso - piperazine or - homopiperazine and reducing the nitroso group. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03088970-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1997494-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7655674-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4117225-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2003231032-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03088970-A3 |
priorityDate | 1961-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 46.