http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-979131-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ff1377f2c7b7a059516979b8d8d5c55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-48 |
| filingDate | 1959-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d71038aef250f9613fc16561935fa06d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34bd06e941733a3a799c656d905d1479 |
| publicationDate | 1965-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-979131-A |
| titleOfInvention | Improvements relating to cyclic sulphone compounds |
| abstract | The invention comprises 3 hydrazino-1, 1-dioxo-tetrahydrothiophenes of the general formula <FORM:0979131/C1/1> and salts and hydrazides thereof, wherein R1, R2 and R3 are the same or different and may be hydrogen, alkyl, aryl, aralkyl, alkaryl, or sulpholane, the sulpholane ring being optionally further substituted for example by alkyl, aryl, hydroxy or hydrazino group. The invention includes such compounds as 3 hydrazino-1, 1-dioxo tetrahydrothiophene, 3 (2121-dimethylhydrazino)-1, 1-dioxotetrahydrothiophene, 2, 4-dimethyl-3-hydrazino-1, 1-dioxotetrahydrothiophene, 3 methyl-3 hydrazino-1, 1-dioxotetrahydrothiophene, NN1-di-3-sulphanyl-hydrazine, N-methyl-N-3-sulphanyl hydrazine, N-phenyl N1-3-sulphanyl hydrazine, 4-hydrazino-sulpholan-3-ol and 3, 4-dihydrazino sulpholane, and salts and hydrazides thereof. The hydrazino compounds are prepared by (1) reacting the hydrazine NHR1NR2R3 in which R1, R2 and R3 are hydrogen, alkyl, aryl or sulpholane, with an unsaturated cyclic sulphone <FORM:0979131/C1/2> which may be further substituted as above, with or without a small quantity of a strong base preferably at a temperature above 50 DEG C. and in the presence of excess hydrazine, (2) reacting the above unsaturated cyclic sulphone with a primary amine and subjecting the product to treatment with nitrous acid and then a reducing agent, (3) reacting a 3-halogeno sulpholane with a hydrazine containing at least one free hydrogen atom, (4) reacting a sulpholanylamine having at least one N-H with chloramine or an alkyl or aryl derivative thereof, and (5) reacting a 3, 4 epoxysulpholane with hydrazine and recovering the 4-hydrazino sulpholan-3-ol. Examples are given in which the above mentioned compounds are prepared by one or other of methods 1, 2, 3 and 5. Also mentioned are the formation of the nitrate, sulphate and oxalate of 3 hydrazino-3-methyl sulpholane, the p-nitrobenzaldehyde derivative of 4 hydrazinosulpholan-3-ol, and the benzaldehyde derivative of N-methyl-N-sulphonyl hydrazine. In general, the hydrazines may be reacted with benzenesulphonyl chloride, and other acyl chlorides, acids, esters, aldehydes, ketones, keto-acids and unsaturated acids. |
| priorityDate | 1959-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 49.