http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-978288-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-82 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-58 |
| filingDate | 1962-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1964-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-978288-A |
| titleOfInvention | New nicotinic acid phenyl-ethylamides and preparations containing them |
| abstract | The invention comprises compounds of the formula <FORM:0978288/C1/1> (wherein R1 and R2 are alkyl radicals each of at most 4 carbon atoms and X, Y and Z are hydrogen or chlorine atoms, or alkoxy radicals of at most 4 carbon atoms, or two of them may represent a methylenedioxy radical, at least one of X, Y and Z being other than hydrogen) and their preparation by reacting nicotinic acid or a functional derivative thereof with the appropriately substituted phenylethylamine. Functional derivatives referred to are azides, esters, mixed anhydrides and halides, the last-named preferably being used as their hydrohalides. Examples are given. Amines of the formula <FORM:0978288/C1/2> are prepared by reduction of the corresponding nitriles, themselves prepared by alkylation of benzyl cyanides substituted in the nucleus by the required groups X, Y and Z. The substituted nicotinamides of the invention, which are stated to have a sedative, tranquilizing and neuroleptic action, may be made up into pharmaceutical compositions with suitable carriers. These may take the form of capsules, dragees, emulsions or tablets. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4514408-A |
| priorityDate | 1961-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.