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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-42
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filingDate 1963-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1964-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-973844-A
titleOfInvention Process for the production of 10-hydroxyhexadec-7-yne-1-oic acid
abstract 10-Hydroxyhexadec-7-yne-1-oic acid is produced by converting 7-chlorohept-1-yne into an organo-metallic compound with n-butyl lithium, reacting this with 1, 2-epoxyoctane to give 1-chloro-9-hydroxypentadec-6-yne, converting this into the corresponding 1-iodo compound with sodium iodide, reacting the iodo compound with excess sodium or potassium cyanide to give 10-hydroxyhexadec-7-yne-1-oic acid nitrile which is then hydrolysed with an aqueous alcoholic solution of an alkali metal hydroxide, the whole synthesis being carried out in the absence of oxygen. The 7-chlorohept-1-yne may be obtained from 1-chloro-5-iodobutane and sodium acetylide in liquid ammonia.
priorityDate 1962-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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