http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-966479-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bf2ba08adb8ed810fa2aafc13dea308 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C65-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C47-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C65-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C65-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C65-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C65-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C65-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C47-57 |
| filingDate | 1963-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1964-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-966479-A |
| titleOfInvention | New substituted salicylic acid derivatives |
| abstract | The invention comprises compounds of general formula: <FORM:0966479/C1/1> wherein X and Y represent hydrogen or halogen atoms or hydroxyl or C1- 3 alkyl or alkoxy radicals, and A is a straight or branched chain saturated or unsaturated aliphatic hydrocarbon radical containing 2 to 4 carbon atoms; and their preparation by (1) treating a compound of formula: <FORM:0966479/C1/2> or an alkali metal salt thereof, with carbon dioxide, (2) treating a compound of formula: <FORM:0966479/C1/3> with an oxidising agent, (3) treating a compound of formula: <FORM:0966479/C1/4> with a hydrohalic acid, (4) in the preceding processes where the p-position to the phenolic hydroxy group is first blocked with a halogen atom this is split off at the end of the reaction by catalytic hydrogenation, and (5) where A in a compound I is unsaturated, forming the corresponding saturated compound by catalytic hydrogenation. Sodium salts of certain products are mentioned. Starting materials obtained are 3-(a -methyl-benzyl)-5-chloro-saligenin by treatment of 2-(a -methyl-benzyl)-4-chlorophenol with aqueous alkaline formaldehyde; hydrogenation yields 3-(a -methyl-benzyl)-saligenin which can also be obtained by lithium aluminium hydride of 3-(a -methyl-benzyl)-salicylic acid; treatment with methyl iodide yields 2-methoxy-3-(a -methyl-benzyl)-benzyl alcohol, the corresponding benzoic acid being obtained by potassium permanganate oxidation. 3-(a -Methyl-benzyl)-5-chloro-salicyl aldehyde is obtained from the corresponding saligenin using m-nitrobenzene-sulphonic acid sodium salt; 3-(a -methyl-benzyl)-salicyl aldehyde is similarly obtained. |
| priorityDate | 1962-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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