http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-966452-A

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_207a93bf1d29029ffcc1a30a439819b8
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70
filingDate 1963-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4fad336065766a442ad4ac62a0cc6db
publicationDate 1964-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-966452-A
titleOfInvention Water dispersible antibiotics
abstract The water-dispersibility of a water-insoluble polypeptide antibiotic is increased by dissolving the antibiotic and a highly water-soluble polymeric material in a non-aqueous solvent such as methanol, ethanol, isopropanol, benzyl alcohol or pyridine and then removing the solvent, preferably by evaporation, to obtain a dry readily water-dispersible complex. The antibiotic may be tyrothricin, tyrocidine or gramicidin and the polymeric material may be a polymer or copolymer of vinyl pyrrolidone, a poly-N-vinyl oxazolidinone or a block copolymer of polyoxyethylene and polyoxypropylene.ALSO:A dry, readily water-dispersible complex of a water-insoluble polypeptide antibiotic and a highly water-soluble polymeric material is obtained by dissolving the antibiotic and the polymeric material in a non-aqueous solvent such as methanol, ethanol, isopropanol, benzyl alcohol or pyridine and then removing the solvent, preferably by evaporation. The antibiotic may be tyrothricin, tyrocidine or gramicidin and the polymeric material may be polyvinyl pyrrolidone, a copolymer of vinyl pyrrolidone and vinyl acetate or vinyl alcohol, a poly-N-vinyl oxazolidinone or a block copolymer of polyoxyethylene and polyoxypropylene.
priorityDate 1963-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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