http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-954213-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a157f5faa443ba5bb3367371f1e2a6c7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-33 |
| filingDate | 1960-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1964-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-954213-A |
| titleOfInvention | New therapeutically active sulphonamides and process for their preparation |
| abstract | The invention comprises monoazo compounds of formula <FORM:0954213/C3/1> wherein R1 is a hydrogen atom or an acetyl group, R is a heterocyclic residue containing either a nitrogen atom and a sulphur atom or two nitrogen atoms and A is an aromatic residue which may be substituted. The compounds are therapeutically active. They are prepared by coupling a diazotised aromatic amine with a compound of formula <FORM:0954213/C3/2> The compounds are light yellow in colour. In examples the preparation of the following compounds is described: 2-(p-aminobenzenesulphonamido) - 4 - methyl - 5 - (p - chlorophenylazo) - thiazole; 2 - (p - aminobenzenesulphonamido) - 4 - methyl - 5 - (phenylazo)-thiazole; 2 - (p - aminobenzenesulphonamido)- 4 - methyl - 5 - (p - tolylazo) - thiazole; 2 - (p-acetylaminobenzenesulphonamido) - 4 - methyl- 5 - (p - chlorophenylazo) - thiazole; 2 - (p - aminobenzenesulphonamido) - 4,6 - dimethyl- 5 - (phenylazo) - pyrimidine; 2 - (p - aminobenzenesulphonamido) - 4 - methyl - 5 - (p-ethoxyphenylazo) - thiazole; 2 - (p - aminobenzenesulphonamido) - 4 - methyl - 5 - (l-naphthylazo) - thiazole; 2 - (p - aminobenzenesulphonamido) - 5 - (p - chlorophenylazo) - thiazole and 2 - (p - aminobenzenesulphonamido)-4-phenyl-5-(p-tolylazo)-thiazole. Compounds of the above formula are therapeutically active and may be used in pharmaceutical compositions. Specified compositions are wound sprayings, ointments for eyes or wounds, aqueous suspensions, aerosols and enterosolvent dragees. The compounds are effective against strepto-, staphylo- and pneumo-cocci and have some action on strains of Staphylococcus aureus haemolyticus. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4406661-A |
| priorityDate | 1959-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.