http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-935602-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d30ad294786868bb6a8b51400e42c51c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5015 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 |
| filingDate | 1961-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1963-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-935602-A |
| titleOfInvention | Sustained release type of pharmaceutical vehicles |
| abstract | A retardant coating composition for oral pharmaceutical dosage forms comprises a mixture of from 93 to 95% by weight of a glyceride of a fatty acid or fatty oil, 1% beeswax and from 4 to 6% of one or more fatty alcohols. Specified glycerides are glyceryl mono- and di-stearate and glyceryl esters of hydrogenated fatty oils containing more than 10 carbon atoms, e.g. castor oil. Specified fatty alcohols are long-chain alcohols of more than 10 carbon atoms, e.g. cetyl, stearyl and myristyl alcohols. The coating may be applied to a tablet or a pellet comprising an inert central core coated with one or more medicament layers in which the medicaments may be the same or different. Such layers may be separated by layers of the retardant coating composition so that the medicaments contained therein are released successively, and the dosage forms may be provided with an outer enteric coating, e.g. of cellulose acetate phthalate or the outermost medicament layer may be uncoated to allow for immediate release of the medicament contained therein. The coatings may be applied by conventional methods, e.g. pan-coating using solutions of the coating materials in volatile solvents. Medicaments specifically referred to include sympathomimetic agents, e.g. amphetamine and isoproterenol, antibiotics, e.g. benzyl penicillin, vitamins, minerals, cardiac agents, and barbiturates, vasodilators, vasoconstrictors, soporifics and stimulants. Examples include dosage units comprising d-amphetamine sulphate and an outer coating of a sedative, e.g. phenobarbital; medicaments which cause visitation in the stomach, e.g. salicylates, ferrous compounds, zoxazolamine and phenylbutazine and isoproterenol in pellets from which a portion of the medicament is released immediately on administration and the remainder is released in portions each hour for ten hours. Specification 837,550 is referred to. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2203336-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2390303-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2390303-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4994279-A |
| priorityDate | 1960-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.